Protein Microarrays for Personalized Medicine

Protein microarrays for personalized medicine.

BACKGROUND Over the last 10 years, DNA microarrays have achieved a robust analytical performance, enabling their use for analyzing the whole transcriptome or for screening thousands of single-nucleotide polymorphisms in a single experiment. DNA microarrays allow scientists to correlate gene expression signatures with disease progression, to screen for disease-specific mutations, and to treat pa...

Personalized Medicine for Gliomas

Personalized medicine for cancer entails tailoring therapy for each patient based on unique features of the patient's tumor; physiologic, molecular, genetic and epigenetic. Our ability to molecularly characterize tumor cells has increased dramatically and shown that there are significant differences between samples from patients with the same tumor type. Given this extensive variability in muta...

Perspectives of personalized medicine in traditional persian medicine

The approach of personalized medicine has received a great deal of attention over the last century, emphasizing attention to the patient rather than the disease. Personalized medicine tries to plan the patient's condition and treatment method by considering the culture, personal preferences and experiences and health beliefs of the person as well as the values and lifestyle of the person, and e...

Advancing Protein Science for Personalized Medicine - 2008-09 Annual Report

Oral delivery of protein drugs: driver for personalized medicine.

The pathogenesis of common diseases, such as metabolic diseases, is caused by the complex and individual interplay of many susceptibility genes, which necessitates both personalized diagnosis and therapy. Small-molecule drugs which adequately address the multiple tissue-specific target proteins affected probably will not become available in near future. In contrast, therapeutic proteins, such a...